UPMC Montefiore Clinical and Translational Research Center

The Montefiore Clinical and Translational Research Center (MUH-CTRC) provides state-of-the-art infrastructure, inpatient and outpatient facilities, specialized equipment, and experienced staff to support clinical and translational research. The MUH-CTRC is located on the 6th floor of UPMC Montefiore and typically has more than 100 research protocols in its portfolio. MUH-CTRC administrative staff maintain rigorous oversight of all studies and assist investigators with every aspect of research from study design and budget development through implementation.

The MUH-CTRC has five inpatient and three outpatient private rooms; an outpatient suite with three beds and treatment chairs; six outpatient examination rooms; interview room; bariatric bed; and sample-processing laboratory. Personnel include research nurses and support staff.

Facilities and Personnel

  • Five inpatient and three outpatient private rooms
  • An outpatient suite with three beds and treatment chairs
  • Six outpatient examination rooms
  • Interview room
  • Bariatric bed
  • A vascular research procedure room (see below)
  • Sample-processing laboratory
  • Research nurses and support staff available

Nursing Services

  • Consultation during protocol development to review feasibility
  • Assistance with development of protocol-specific standard operating procedures (SOPs)
  • Execution and completion of pilot protocols, phase I, II, III clinical trials
  • Protocol conduct and support
  • Phlebotomy and intravenous catheter placement
  • Vascular device access
  • Collection and processing of pharmacodynamic and pharmacokinetic specimens
  • Administration of oral, intramuscular, subcutaneous, and intravenous investigational agents (including chemotherapy and biologic agents) by certified oncology nurses
  • Electrocardiogram services (single and sequential)
  • Frequent vital signs including pulse oximetry
  • Collection, processing, and shipping of safety laboratory specimens
  • Patient education
  • Acute and emergency care with full support of a UPMC code team

Vascular Services and Equipment

The MUH-CTRC provides specialized expertise in vascular research procedures. A registered vascular sonographer performs all vascular testing, image interpretation, and data analysis. The sonographer can also assist investigators in preparation of programs and presentations.

  • Brachial and radial artery flow mediated dilation (FMD) with and without nitroglycerin
  • Carotid artery intima-media thickness (CIMT)
  • Carotid plaque assessment (detection and characterization)
  • Peripheral arterial tone for measuring endothelium-mediated changes in vascular tone (EndoPAT)
  • Arterial waveform analysis (PWA)
  • Parameters of vascular stiffness, augmentation index, pulse wave velocity (PWV)
  • Quipu Cardiovascular Suite software
  • GE LOGIQ S8 Ultrasound with Advanced Vascular Data Acquisition System
  • SphygmoCor Arterial Waveform Analysis System
  • EndoPAT 2000


UPMC Montefiore Hospital, 6NE
200 Lothrop Street
Pittsburgh, PA 15213

Hours of Operation

Monday, Tuesday: 6:30 a.m. to 9 p.m. 
(Additional hours available by request)
Wednesday and Thursday: Open 24 hours
Friday: close at 5 p.m.


Jill Huwe, Nurse Manager
Phone: 412-648-6530
Fax 412-802-8668
Email: huwejm@upmc.edu,